Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0308042
PubChem CID
Molecular Formula
C7H9N3O
Molecular Weight
151.169 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
YQSHPGUURTXVDV-UHFFFAOYSA-N
InChI
InChI=1S/C7H9N3O/c1-5-6(7(11)10-8)3-2-4-9-5/h2-4H,8H2,1H3,(H,10,11)
IUPAC Name
2-methylpyridine-3-carbohydrazide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

11 11 0 0 0 0 0 0 0 0999 V2000
0.2713 -2.2284 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.6662 -1.0574 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.1490 -1...

Experimental Data

Activity Data

Target Ion Channel
P2X purinoceptor 7
Uniprot Accession Number
Function
Modulator
Species
Mus musculus (Mouse)
IC50
IC50: 49.5 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
Room Temperature
Test Method
Fluorometric Imaging Plate Reader (FLIPR) assay
Test Species
1321N1 cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

DOI
N/A (Not available)
URL
N/A (Not available)
PMID
N/A (Not available)
Patent
US10053463

Computed Properties

Heavy Atom Count
11
Rotatable Bonds
1
logP
-0.0065
Complexity
40.6276
TPSA (Ų)
68.01
H-Bond Donors
2
H-Bond Acceptors
3
Ring Count
1
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